National edeposit has been developed to ensure its content is available to the widest possible audience, including users of assistive technology or accessibility features, and strives to maintain compliance with W3C’s Web Content Accessibility Guidelines (WCAG) 2.1 at Level AA.

Where publishers have nominated onsite-only access to electronic content, however, access is provided through a secure browser onsite at the National Library of Australia or a state or territory library to prevent unauthorised downloading or copying. Users of National edeposit requiring the use of assistive technology beyond the built-in screen magnification and text adjustment functionality for this restricted content, are asked to contact their member library for an accessible copy.